The heart in the marathon
Cardiovascular stress biomarker assessment of middle-aged non-athlete marathon runners The cardiovascular security of marathon runs remains unclear.This study examined the impact of a marathon on the profile of biomarkers for cardiovascular burdens associated with transthoracic echocardiography.Thirty-three healthy male amateur runners, which were ≥ 50 years old (average age 57 ± 7 years), were examined. Venous blood samples were won in front of the marathon shortly after the race, 2-4 days and 7 days after the marathon.The plasma concentrations of highly sensitive heart troponin I (HS-CTNI) and endothelin-1 were measured.The N-terminal Pro-B-type natriuretic peptide was measured using electrochemiluminescence. Each participant had a transthoracic echocardiography before and immediately after the race. It showed a strong increase in biomarkers after the race, which was normalized after 2-4 days and remained in the normal range after 7 days. Runners with intensive training programs (> 169 km / month) after the race had a lower HS-CTNI. There were a decline in the left atrial volume volume and an increase in the maximum right atrial volume. Changes in the Doppler indices of the diastolic function were observed, which indicate a change in left ventricular relaxation. A marathon is associated with a strong and significant increase in biomarkers.
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